An EU programme of COVID-19 convalescent plasma collection and transfusion


Guidance on collection, testing, processing, storage, distribution and monitored use


This document has been endorsed by the Competent Authorities for Substance of Human Origin
Expert Group (CASoHO E01718) following consultation of the competent authorities for blood and
blood components and by the European Centre for Disease Prevention and Control. While this
document is not legally binding, it aims to facilitate a common approach across EU Member States
to the donation, collection, testing, processing, storage, distribution and monitoring of
convalescent plasma for the treatment of Covid-19. This document is without prejudice to the
requirements of the Union blood legislation, any more stringent national measures in place at
Member State level and national requirements on the use of this treatment, all of which continue
to apply. This guidance will be updated as needed, in line with scientific developments.

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