Behnam Sadeghi

Behnam Sadeghi, M.D.

Sweden

Dr Behnam Sadeghi is physician and did his PhD in transplantation Immunobiology in 2009 at Karolinska Institute, Sweden. Since then Behnam’s research and practice concentrated in the field of cell therapy and regenerative medicine both in clinical practice and experimental models. Dr Sadeghi established and applied decidua stromal cells (DSC) for the treatment of steroid refractory GVHD and other acute inflammatory disorders in man. Other cell therapy modalities including bone marrow, adipose derived mesenchymal stromal cells (BM, Ad-MSC) are among his research interest. Dr Sadeghi is head of Translational Cell therapy Research group (TCR) at the department of CLINTEC, Karolinska Institute, Stockholm, Sweden.

Videos

Join us at the Global Regenerative Congress 2020 in Dubai

Work Experience

2016-Present Editorial board of ember of AIMS Cell and Tissue Engineering
2014-Present Member of Society for Immunotherapy of Cancer, SITC
2013-Present Member of International Society for Cellular Therapy, ISCT
2013-Present Member of International Placenta Stem cell Society, IPLASS
2009-2015 Member of American Society of hematology, ASH.
2009-2011 Member of European Hematology Association EHA
2004- 2005 Member of American Society of Gene Therapy
2000-2004: Researcher and internal manager of rheumatology research center,
Tehran University of medical sciences. Tehran, Iran.
2002 Executive secretary of “9th Annual congress of rheumatology
research center “Osteoporosis”. February 6-7, 2003, Tehran,
Iran.
1999-2002: Researcher and research project designer of hematology, oncology
& BMT research center, Tehran University of medical sciences.
Tehran, Iran.
3
1999-2002: Member of scientific committee of hematology, oncology & BMT
research center, Tehran University of medical sciences. Tehran,
Iran.
1990-2000: Head of public and scientific relations and researcher of
cardiovascular research center, Tehran University of medical
sciences. Tehran, Iran.
1994-1996: Student research advisor of research undersecretary, ministry of
health and medical education, Tehran, Iran.
1995: Executive secretary of the national research festival for medical
sciences and exhibition (Razi Festival). Tehran, Iran.
1994 Member of scientific committee of the first Iranian medical
students’ research festival Shiraz University of medical sciences,
Shiraz, Iran.
1994: Member of administrative committee of the 8th annual Iranian
medical students’ congress. Babol University of medical sciences,
Babol, Iran.
1993-1994: Vice-President and secretary of the students’ scientific research
center (SSRC) of Tehran University of medical Sciences.
1989-1993: Head of the office for coordinating medical students research
activity in Tehran University of medical sciences.

Education

2018- Present Senior Researcher, Karolinska Institute, Department of CLINTEC.
2014- 2018 Assistant Professor, Karolinska Institute, Department of Lab. Medicine.
2011- 2013 Postdoc, Karolinska Institute, Department of Lab. Medicine.
2009- 2011 Postdoc, Karolinska Institute, Department of Lab. Medicine.
2005- 2009 PhD, Karolinska Institute, Department of Lab. Medicine.
1988- 1995 M.D. Tehran University of Medical Sciences, Tehran, Iran.

Publications

Gianluca Moretti, Bita Khoein, Lena Klingspor, Magnus Westgren, Jonas Mattsson
and Olle Ringdén. Long-term follow-up of a pilot study using placenta-derived
decidua stromal cells for severe acute graft-versus-host disease. Biol Blood Marrow
Transplant. 2019 Jun 4. pii: S1083-8791(19)30359-3. doi:
10.1016/j.bbmt.2019.05.034. [Epub ahead of print].
2019 Olle Ringdén, Ariane Boumendil, Myriam Labopin, Jonathan Canaani,
Dietrich Beelen, Gerhard Ehninger, Dietger Niederwieser, Jurgen Finke, Matthias
Stelljes, Armin Gerbitz, Arnold Ganser, Nicolaus Kröger, Lothar Kantz, Arne Brecht,
Bipin Savani, Behnam Sadeghi, Mohamad Mohty, Arnon Nagler. Outcome of
Allogeneic Hematopoietic Stem Cell Transplantation in Patients Age >69 Years with
Acute Myelogenous Leukemia: On Behalf of the Acute Leukemia Working Party of
the European Society for Blood and Marrow Transplantation. Biol Blood Marrow
Transplant. 2019 Jun 7. pii: S1083-8791(19)30362-3. doi:
10.1016/j.bbmt.2019.05.037. [Epub ahead of print].
2019 Imani M, Kazemi S, Saviz M, Farahmand L, Sadeghi B, Faraji-Dana R.
Morphological Changes Induced By Extremely Low-Frequency Electric Fields.
Bioelectromagnetics. 2019 Sep;40(6):375-390. doi: 10.1002/bem.22195. Epub 2019
Jun 3.
2019 Ringden O, Remberger M, Gustafsson B, Moretti G, Mattsson J, Winiarski J,
Sadeghi B. The Outcome of Allogeneic Hematopoietic Stem Cell Transplantation for
Inherited Diseases Is Influenced by HLA Match, Year of Transplantation, and
Immunized Female Donor. Transplantation. 2019 Jun;103(6):1247-1252. doi:
10.1097/TP.0000000000002481

 

2018 Ringden O, Baygan A, Remberger M, Gustafsson B, Winiarski J, Khoein
B, Moll G, Klingspor L, Westgren M, Sadeghi B. Placenta-Derived Decidua Stromal
Cells for Treatment of Severe Acute Graft-Versus-Host Disease. Stem Cells Transl
Med. Stem Cells Transl Med. 2018 Apr;7(4):325-331.
2018 Aronsson-Kurttila W, Baygan A, Moretti G, Remberger M, Khoein B, Moll
G, Sadeghi B, Ringdén O. Placenta-Derived Decidua Stromal Cells for Hemorrhagic
Cystitis after Stem Cell Transplantation. Acta Haematol. 2018 Feb 7;139(2):106-114.
2018 Ringdén O, Sadeghi B, Moretti G, Finnbogadottir S, Eriksson B, Mattsson
J, Svahn BM, Remberger M. Long-term outcome in patients treated at home during
the pancytopenic phase after allogeneic haematopoietic stem cell transplantation. Int J
Hematol. 2018 Apr;107(4):478-485.
2018 Ringdén O, Labopin M, Sadeghi B, Mailhol A, Beelen D, Fløisand
Y, Ghavamzadeh A, Finke J, Ehninger G, Volin L, Socié G, Kröger N, Stuhler
G, Ganser A, Schmid C, Giebel S, Mohty M, Nagler A. What is the outcome in
patients with acute leukaemia who survive severe acute graft-versus-host disease? J
Intern Med. 2018 Feb;283(2):166-177.
2017 Britt Gustafsson, Per Frisk, Attilla Szakos, Behnam Sadeghi, Olle Ringdén,
Britt-Marie Frost; Successful treatment with placenta-derived decidual stromal cells
in a pediatric patient with life-threatening acute gastro-intestinal graft-versus-host
disease. Pediatr Transplant. 2017 Aug;21(5).
2017 Baygan A, Aronsson-Kurttila W, Moretti G, Tibert B, Dahllöf G, Klingspor L,
Gustafsson B, Khoein B, Moll G, Hausmann C, Svahn BM, Westgren M, Remberger
M, Sadeghi B, Ringden O; Safety and Side Effects of Using Placenta-Derived
Decidual Stromal Cells for Graft-versus-Host Disease and Hemorrhagic Cystitis.
Front Immunol. 2017 Jul 11;8:795.
2017 Olle Ringden, Myriam Labopin, Christoph Schmid, Behnam Sadeghi,
Emmanuelle Polge, Johanna Tischer, Arnold Ganser, Mauricette Michallet, Lothar
Kanz, Rainer Schwerdtfeger and Arnon Nagler, Mohamad Mohty. Sequential
chemotherapy followed by reduced-intensity conditioning and allogeneic
haematopoietic stem cell transplantation in adult patients with relapse or refractory
acute myeloid leukaemia: a survey from the Acute Leukaemia Working Party of
EBMT. Br J Haematol. Br J Haematol. 2017 Feb;176(3):431-439.
2016 Manuchehr Abedi-Valugerdi; Johanna Wolfsberger; Preethi R Pillai; Wenyi
Zheng; Behnam Sadeghi; Ying YZhao and Moustapha Hassan. Suppressive effects
of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory
neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice.
International Immunopharmacology. 2016 Nov; 40:41-49.
2015 Sadeghi B., Heshmati Y., Khoein B., Kaipe H., Uzunel M., Walfridsson J.,
Ringdén O. Xeno-immunosuppressive properties of human decidua stromal cells in
mouse models of alloreactivity, in vitro and in vivo. Cytotherapy. 2015
Dec;17(12):1732-45.

Workshops and Courses

2009 “Digital Photomicrography”, KTH/Royal Institute of Technology and
Karolinska Institute, Stockholm, Sweden.
2007 “Techniques in Cellular Immunology”, Uppsala University, Uppsala,
Sweden.
2007 “Methodologies in Molecular Medicine”, Karolinska Institute,
Stockholm, Sweden.
2005-6 “Flow cytometry; Theory to Application”, Beckton Dickenson Co. and
Karolinska Institute, Stockholm, Sweden.
2005 “Laboratory Animal Sciences”, Karolinska Institute, Stockholm,
Sweden.
2004 “Bioinformatics Essentials”, Genetic Research Center, University of
Social Welfare & Rehabilitation, Tehran, Iran.
2002 “Training Course on Good Clinical Practice GCP”, TDR/WHO
Clinical Co-coordinator (Geneva, Switzerland) and Research deputy of
Tehran University of Medical Sciences, Tehran, Iran.
2002 “Scientific Writing”, by Stuart Spencer, Senior editor of the Lancet,
Tehran University of Medical sciences, Tehran, Iran.
2001 “Introduction to Practical and Theoretical Fundamentals of
Molecular Biology Methods”, Genetic Research Center, University of
Social Welfare & Rehabilitation, Tehran, Iran.
2
2001 “1st Human Genetic Workshop for Specialists at University Hospital”,
Health Faculty and Health Research Institute, Genetic Department,
Tehran University of Medical sciences, Tehran, Iran.
2000 “Application of Molecular Methods in Immunogenetics”, National
Research Center for Genetic Engineering & Biological Technology,
Tehran, Iran.
1990-1991 Research methodology, department of Social Medicine, Tehran
University of Medical Sciences, Tehran, Iran.

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