Soft tissue

A graduate of MU-Sofia became “Student of the Year” for the whole country

Dr. Diyan Ganev, who graduated a week ago from the Medical Faculty of MU-Sofia with excellent grades and honors from the academia, yesterday received another valuable certificate – a diploma for the award “Student of the Year” for 2020, informed by MU-Sofia. Dr. Ganev is Sales manager in the Global Regenerative Trade. The graduate of …

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Platelet-rich plasma (PRP) as therapy for cartilage, tendon and muscle damage – German working group position statement

Platelet rich plasma (PRP) is widely used in regenerative medicine and especially in orthopaedic sport medicine [14, 34, 45]. Basic science studies show many positive effects of PRP in vitro and in vivo on many cells of the musculoskeletal system, e.g. chondrocytes, tenocytes or muscle cells [5, 6, 21, 33, 41]. However, the quality of the available literature remains limited, both …

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(The Lancet) Effect of platelet-rich plasma on healing tissues in acute ruptured Achilles tendon: a human immunohistochemistry study

Platelet-rich plasma (PRP), an autologous derivative of whole blood that contains a supraphysiological concentration of platelets, is thought to invoke an earlier and improved tissue healing response. This notion has been supported by in-vitro and animal studies in bone, cartilage, tendon, and muscle. To our knowledge no published study exists of the effects of PRP in human tissues in vivo. The aim of our study was to investigate the response of ruptured Achilles tendon treated with PRP.

Can PRP effectively treat injured tendons?

PRP is widely used to treat tendon and other tissue injuries in orthopaedics and sports medicine; however, the efficacy of PRP treatment on injured tendons is highly controversial. In this commentary, I reason that there are many PRP- and patient- related factors that influence the outcomes of PRP treatment on injured tendons. Therefore, more basic science studies are needed to understand he mechanism of PRP on injured tendons. Finally, I suggest that better understanding of the PRP action mechanism will lead to better use of PRP for the effective treatment of tendon injuries in clinics.

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