Gamze Köse – Stem cell usage in hard tissue engineering

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There are a large number of people suffering from an organ or tissue loss due to injury, infection, or disease. Currently, major approaches to solve this problem are surgical reconstruction, transplantation or use of prosthesis. Although these therapies have saved and improved countless lives, they remain imperfect solutions due to occurrence of infection, chronic irritation, donor shortages, tissue rejection, and longer-term complications such as development of malignant tumor.

Tissue engineering, the development of cell seeded 3D biomaterials for introduction to the defect area is the current solution for all of the problems mentioned above. The success of tissue engineering relies on the ability to generate complex, cell seeded 3D structures, and methods that enable precise engineering of the scaffold architecture having a critical role for functional tissue development.

Stem cell sources have extensively been used for the treatment of tissue defects since they have the capacity to originate a wide range of tissues. MSC can be isolated from many tissues including bone marrow, adipose tissue, placenta, umbilical cord or umbilical cord blood. Also, dental stem cells isolated from human dental pulp, periodontal ligament, periapical follicle and mandibular bone marrow are expressing mesenchymal stem cell surface markers, and they represent a stem cell source for tissue-engineering applications.

Why is the knowledge in this video important? And why attend another event of the Academy?

The Key opinion Leaders of the Academy have a sum of more than 200 years of clinical practice and scientific studies. They have reached a moment of their careers when there is nothing ahead of them but only their potential to create new knowledge.

For the people behind them it is so simple as just to learn from them. The Academy is giving this opportunity to its members – a simple buy and watch process where the beneficiaries are everybody.

Why attend an Academy event? Come and speak with the Academy leaders, learn new protocols, practices, inspiration to do better and more.

Upon completion of the whole panel you will be issued a Certificate of Acknowledgement for completing the online education form of the Global Regenerative Academy.





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