M.D. Abbas Khadra – Combination of Cord derived stem cells with PRP (platelet rich plasma) in the treatment of erectile dysfunction.

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Erectile dysfunction is one of the most common causes of morbidity in male patients, with a prevalence of 50-60% in men aged 40-70 years. The main cause involved in the pathophysiology of erectile dysfunction is vascular damage related to endothelial and neuronal injury. In the past decades, great interest has been shown in the development of new therapies for erectile dysfunction, the most important of which is stem cell therapy. Stem cell therapy has generated promising results in numerous preclinical trials in animal models, which has led to trials in humans. The interest in stem cell therapy is justified by their capability to differentiate into specific damaged tissues, including endothelium and nervous tissue, and induction of host own cell proliferation. Recent study treating erectile dysfunction in post radical prostatectomy for prostate cancer with fat derived stem cells, showed a significant improvement in erectile function (Haahr et al, 2017). Platelet Rich Plasma (PRP) has been injected into the corpora cavernosa (“P”Shot) for the treatment of erectile dysfunction in various clinics across the world but the benefits not assessed in clinical trials. In this small observational trial we assess the effects of injecting PRP with cord derived stem cells in the treatment of erectile dysfunction.

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