Prof. Stefano Zanasi


Professor Stefano Zanasi is a renowned orthopaedic surgeon and specialist in regenerative surgery and biotechnology. He practices internationally including at 9 Harley Street and the Weymouth Street Hospital in London. He specialises in advanced hip surgery and knee surgery, including revision arthroplasty and robotic-assisted techniques. He is also a hand surgery and microsurgery specialist and performs around 950 operations a year.
Advanced Knee surgery
• Regenerative Surgery – in particular in the treatment of lower limb osteoarthritis through biological resurfacing of resorbable scaffolds perfused with combined mesenchymal stem cells in alternative to traditional implant arthroplasty
• Concurrent bilateral or isolated unilateral partial knee arthroplasty (medial or lateral UNI, PFJ, BiUNI, bicompartmental knee arthroplasty)
• Customised knee implant arthroplasty
• Robotic knee implant arthroplasty
• Revision total knee arthroplasty
Advanced Hip surgery
• Concurrent bilateral or unilateral MIS neck preservation hip arthroplasty
• Customised primary or revision hip implant arthroplasty
• Robotic hip implant arthroplasty
• Revision total hip arthroplasty
Regenerative medicine prolotherapy using combined stem cells
Professor Zanasi graduated with honours from the University of Modena in his native Italy in 1986 before undertaking further training and gaining post-graduate qualifications in Orthopaedics and Traumatology. He has published extensively, with his research on minimally invasive resurfacing implant arthroplasty, tissue engineering and biotechnologies being published in 146 journals in Italian, French and English, and three books.
Professor Zanasi has been appointed to a number of senior positions in hospitals where he has worked and has held professorships in Florence and currently in Bologna. He also serves as Technical Consultant for the Court of Modena, as well as performing consultancy work for major companies developing biotechnologies.


• Advanced knee surgery
• Osteoarthritis of the knee and lower leg
• Regenerative medicine / regenerative surgery
• Robotic knee implant arthroplasty
• Robotic hip implant arthroplasty
• Revision total hip arthroplasty (RThA)
• Prolotherapy with combined stem cells

Hesperia Hospital, Modena, Emilia-Romagna, Italy.
Contact for One on One clinical training
Scientific Board Member
Mail: [email protected]
Phone: +1 (954) 716-2140


Orthopaedic Surgeon, Freelance (1989 – present)

 Orthopaedic Division of the Civilian Hospital of Vignola, Hospital of Vignola (1997 – 2001)

Vice Chief

Civilian Hospital of Castelfranco E, Hospital of Castelfranco (1993 – 1997)

Orthopaedic Assistant,

Orthopaedic and Traumatology Division of the Civil Hospital of Modena, Hospital of Modena (1991 – 1992)

Assistant physician


Laurea, Universita degli Studi di Modena e Reggio Emilia

(1980 – 1986)

 Specialisation in Orthopaedics Grade 50/50 e Lode, University of Modena 

(1986 – 1991)

Professor in Orthopaedics, AUSL/University of Modena

(1991 – 1995)

Professor of Biotechnology in the elective course of “Regenerative Medicine” at the University of Bologna – Italy School of Medicine & Surgery



Zanasi S, Zmerly H. Customised three-dimensional printed revision acetabular implant for large defect after failed triflange revision cup.

BMJ Case Rep. 2020 May 25;13(5):e233965. doi: 10.1136/bcr-2019-233965. PMID: 32457031; PMCID: PMC7253004.

Zanasi S. Innovations in total knee replacement: new trends in operative treatment and changes in peri-operative management.

Eur Orthop Traumatol. 2011 Jul;2(1-2):21-31. doi: 10.1007/s12570-011-0066-6. Epub 2011 Jul 13. PMID: 21892363; PMCID: PMC3150806.

Zanasi S. Minimally invasive computer-assisted total knee arthroplasty through a subvastus approach.

Orthopedics. 2006 Oct;29(10 Suppl):S142-4. Erratum in: Orthopedics. 2007 Apr;30(4):327. PMID: 17407942.


Hollander AP, Dickinson SC, Sims TJ, Brun P, Cortivo R, Kon E, Marcacci M, Zanasi S, Borrione A, De Luca C, Pavesio A, Soranzo C, Abatangelo G. Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees.

Tissue Eng. 2006 Jul;12(7):1787-98. doi: 10.1089/ten.2006.12.1787. PMID: 16889509.

Marcacci M, Berruto M, Brocchetta D, Delcogliano A, Ghinelli D, Gobbi A, Kon E, Pederzini L, Rosa D, Sacchetti GL, Stefani G, Zanasi S. Articular cartilage engineering with Hyalograft C: 3-year clinical results.

Clin Orthop Relat Res. 2005 Jun;(435):96-105. doi: 10.1097/01.blo.0000165737.87628.5b. PMID: 15930926.

Pavesio A, Abatangelo G, Borrione A, Brocchetta D, Hollander AP, Kon E, Torasso F, Zanasi S, Marcacci M. Hyaluronan-based scaffolds (Hyalograft C) in the treatment of knee cartilage defects: preliminary clinical findings.

Novartis Found Symp. 2003;249:203-17; discussion 229-33, 234-8, 239-41. PMID: 12708658.

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