Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus

Vaginal atrophy is a common condition among peri- and post-menopausal women. Symptoms of vaginal dryness, pruritus, irritation, loss of subcutaneous fat, sparse pubic hair and dyspareunia occur due to decreased estrogen level. Estrogen-based treatments are effective. But many patients are reluctant to be treated due to health concerns. As alternatives, we explored the efficacy of platelet-rich plasma (PRP) and lipofilling.

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Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases

MSCs, also called mesenchymal stromal cells, are a subset of nonhematopoietic adult stem cells that originate from the mesoderm. They possess self-renewal abilities and multilineage differentiation into not only mesoderm lineages, such as chondrocytes, osteocytes, and adipocytes, but also ectodermic and endodermic cells [8–10]. MSCs can be harvested from several adult tissues, such as bone marrow, menstrual blood, adipose tissue, the umbilical cord, and placenta.

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The O-Shot: Platelet Rich Plasma Therapy (PRP) For Urinary Incontinence

The O-Shot is a noninvasive and mostly painless treatment for urinary incontinence as well as other women’s health conditions such as vaginal dryness and post-natal rehabilitation.

If you’ve heard of the vampire facial – made famous by Kim Kardashian, you probably know that the viral aesthetic treatment uses platelet rich plasma therapy (PRP) as an attempt to rejuvenate the skin.

Similarly, the O-Shot – short for “Orgasm Shot” – is a PRP treatment that is aimed at rejuvenating the sensations in both the clitoris and G-Spot by extracting PRP from a woman’s own blood and injecting it directly into the vulva.

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Can Bone Marrow Derived Stem Cells be Used to Regenerate Ovaries?

These findings serve as a proof of concept for the ability of residual quiescent follicles of damaged ovaries to produce competent oocytes in an adequate ovarian environment but should not be restricted to the limited population of young cancer patients. In fact, a small pool of dormant primordial follicles remains even in the non-functional ovaries of menopausal women and patients diagnosed with premature ovarian insufficiency due to several causes.

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The O-Shot® and Other Uses of PRP (Platelet-Rich Plasma)

Well over ten years ago, medical scientists began to realize that a specific “fraction” of human blood contained special growth factors and healing-inducing properties. This portion of blood, known as Platelet-Rich Plasma (PRP), is devoid of red blood cells but contains blood serum. It is what’s responsible for blood clotting and tissue healing. In everyday life, we know PRP as that yellow goo around a scab from whence healing generates. In addition to speeding healing, platelet rich plasma also contains a significant array of growth factors that make it an enhancer of function of the tissue areas that it comes into contact with.


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