Stem cells for knee issues? Can they help?

There are lots of different types of treatments out there that are called “knee stem cells,” but few involve any actual stem cells. For example, a common one is called an “umbilical cord” stem cell therapy, but this is a scam. Why? Our lab and several others has done this research and shown that the umbilical cord products being used by these clinics contain no actual mesenchymal stem cells (MSCs), despite claims to the contrary (1-3). You will have to log in or register to view the full content.

A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia. PRP is a biological product defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. You will have to log in or register to view the full content.

Can PRP effectively treat injured tendons?

PRP is widely used to treat tendon and other tissue injuries in orthopaedics and sports medicine; however, the efficacy of PRP treatment on injured tendons is highly controversial. In this commentary, I reason that there are many PRP- and patient- related factors that influence the outcomes of PRP treatment on injured tendons. Therefore, more basic science studies are needed to understand he mechanism of PRP on injured tendons. Finally, I suggest that better understanding of the PRP action mechanism will lead to better use of PRP for the effective treatment of tendon injuries in clinics.

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Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus

Vaginal atrophy is a common condition among peri- and post-menopausal women. Symptoms of vaginal dryness, pruritus, irritation, loss of subcutaneous fat, sparse pubic hair and dyspareunia occur due to decreased estrogen level. Estrogen-based treatments are effective. But many patients are reluctant to be treated due to health concerns. As alternatives, we explored the efficacy of platelet-rich plasma (PRP) and lipofilling.

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PRP for Acne Scars

Given that most people between the ages of 18 to 30 get acne, it is typically considered the bane of puberty. However, some people can continue to get acne well into their 40s and 50s. And, PRP for acne scars can help. While acne by itself is an annoying condition, the marks and scars left behind can cause the skin to look severely flawed. It can also take away from a person’s confidence.

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The O-Shot: Platelet Rich Plasma Therapy (PRP) For Urinary Incontinence

The O-Shot is a noninvasive and mostly painless treatment for urinary incontinence as well as other women’s health conditions such as vaginal dryness and post-natal rehabilitation.

If you’ve heard of the vampire facial – made famous by Kim Kardashian, you probably know that the viral aesthetic treatment uses platelet rich plasma therapy (PRP) as an attempt to rejuvenate the skin.

Similarly, the O-Shot – short for “Orgasm Shot” – is a PRP treatment that is aimed at rejuvenating the sensations in both the clitoris and G-Spot by extracting PRP from a woman’s own blood and injecting it directly into the vulva.

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Hair Loss Got You Down? Platelet-Rich Plasma May Regrow It

About 50 million American men and 30 million women have male- or female-pattern baldness. It can begin early in life, but is much more common after the age of 50, when more than 50 percent of men will experience some kind of hair loss.However, an emerging treatment — platelet-rich plasma (PRP) therapy — appears to help regrow lost hair. And, there are virtually no side effects from PRP, except for a mild feeling of pressure at the injection site.

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Platelet-Rich Plasma and Treatment of Erectile Dysfunction: Critical Review of Literature and Global Trends in Platelet-Rich Plasma Clinics

Intracavernosal injection of platelet-rich plasma (PRP) as a treatment for erectile dysfunction (ED) is an emerging practice that warrants awareness among primary care physicians and urologists alike. Epidemiologic studies have shown that ED is a highly prevalent condition, affecting more than 300 million men globally, and the use of regenerative medicine, such stem cells, to reverse ED is highly desired.1 In the current era of consumerism, increasing numbers of patients are demanding novel and innovative treatment options. There is a trend toward the global emergence of clinics offering PRP as a treatment for ED for many desperate and vulnerable men; however, despite the introduction and commercialization of this therapy, there remains little evidence to support its use and guide patient or clinician in the decision making process.

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The O-Shot® and Other Uses of PRP (Platelet-Rich Plasma)

Well over ten years ago, medical scientists began to realize that a specific “fraction” of human blood contained special growth factors and healing-inducing properties. This portion of blood, known as Platelet-Rich Plasma (PRP), is devoid of red blood cells but contains blood serum. It is what’s responsible for blood clotting and tissue healing. In everyday life, we know PRP as that yellow goo around a scab from whence healing generates. In addition to speeding healing, platelet rich plasma also contains a significant array of growth factors that make it an enhancer of function of the tissue areas that it comes into contact with.


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Influence of the PRP injections concentration of effects.

PRP stands for platelet-rich plasma. This is concentrated blood platelets in the patient’s own plasma. To create this, the doctor takes blood and spins it in a centrifuge to concentrate the platelets.
The idea behind PRP injections is that platelets have growth factors that they release to aid healing. So if you cut yourself, the platelets clot the blood and also release growth factors to help the cut heal. Hence, PRP can help injured tissues heal.

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