urology

Mesenchymal Stem Cell Therapy of Male Infertility

Nowadays mesenchymal stem cell (MSC) therapy offers a broad spectrum of treatment of different conditions, including male infertility. Lots of studies suggest that injection of MSC promotes differentiation of germ cells and/or stimulates gonadal tissue development. Currently, there are plenty of MSC therapies of azoospermia which have been studied on animal models and demonstrated good results. Most of the studies were conducted using MSC derived from adipose tissue, the bone marrow, and umbilical cord. Despite the fact that this type of treatment in humans is not established as a first choice option, the use of these techniques gives us hope for a gradual introduction into our daily practice.

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Platelet-Rich Plasma and Treatment of Erectile Dysfunction: Critical Review of Literature and Global Trends in Platelet-Rich Plasma Clinics

Intracavernosal injection of platelet-rich plasma (PRP) as a treatment for erectile dysfunction (ED) is an emerging practice that warrants awareness among primary care physicians and urologists alike. Epidemiologic studies have shown that ED is a highly prevalent condition, affecting more than 300 million men globally, and the use of regenerative medicine, such stem cells, to reverse ED is highly desired.1 In the current era of consumerism, increasing numbers of patients are demanding novel and innovative treatment options. There is a trend toward the global emergence of clinics offering PRP as a treatment for ED for many desperate and vulnerable men; however, despite the introduction and commercialization of this therapy, there remains little evidence to support its use and guide patient or clinician in the decision making process.

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